Improving clinical trial enrollment to help accelerate time to market for new therapeutics: a case study

A large pharmaceutical organization wanted to evaluate how Quest Diagnostics^® could expand access to physicians who could help enroll patients into trials for multiple myeloma.

The organization was looking to utilize the leading diagnostic provider’s extensive network of physicians to:

• Expand their network of known sites to additional physicians who might serve as Principal Investigators (PIs)

• Identify qualified patients for upcoming clinical trials

The approach: data-driven analysis of physicians and patient populations

Using the current physician list from Quest as a model profile, we were able to:

• Uncover active research physicians who were previously unknown to the pharmaceutical company

• Identify those active research physicians who could potentially participate or provide patient referrals in multiple myeloma clinical trials

The results: improved network for clinical trials

By leveraging Quest Diagnostics relationships with half the country’s physicians and hospitals, the pharmaceutical company was able to identify:

• Physicians with the appropriate patient population who had experience with clinical trials

• A validated patient volume for the existing PIs

• 3 distinct referral networks for clinicians and sites

– Tier 1: Potential new trial sites

– Tier 2: Current sites with medically profiled patients

– Tier 3: Potential referring physicians

This added over 1,000 physicians to approach for clinical trial participation or physician referral to study sites.